The Agilent 1290 Infinity Flexible Cube module has enabled a fully automated online SPE extraction LC/MS/MS method for ng/L level detection and quantitation of 34 trace organic compounds (pharmaceuticals, personal-care products, pesticides, perfluorinated compounds and so forth) in a wide variety of water sources. It requires only 1.7 mL of sample and provides a cycle time less than 15 minutes, enabled in part by the simultaneous positive and negative ionization feature of the Agilent 6460 Triple Quadrupole LC/MS. The automated online sample preparation embodied in this method provides unparalleled throughput and reproducibility, as well as time, labor, and solvent savings. Agilent 1200 系列液相色譜－芯片／質譜系統(tǒng)