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50489.1活化凝血因子5(FACTOR Va)活性比色法
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2018-11-08 10:00 1105閱讀次數(shù)
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主要用途活化凝血因子5(FACTORVa)活性比色法定量檢測(cè)試劑是一種旨在通過活化凝血因子X(FXa)及其輔因子活化凝血因子(FVa),激活凝血酶,進(jìn)而水解多肽化合物底物H-D-Phe-Pip-Arg-pNA,釋放黃色對(duì)硝基苯胺,產(chǎn)生吸光峰值的變化,即采用比色法來測(cè)定血液樣品中活化凝血因子活性的權(quán)威而經(jīng)典的技術(shù)方法。該技術(shù)經(jīng)過精心研制、成功實(shí)驗(yàn)證明的。其適用于各種血漿樣品(動(dòng)物、人體等)活化凝血因子5的活性檢測(cè)。產(chǎn)品嚴(yán)格無菌,即到即用,操作簡(jiǎn)捷,性能穩(wěn)定。技術(shù)背景凝血因子5(FactorV)是維生素K非依賴性的不穩(wěn)定性單鏈糖蛋白,由肝組織、內(nèi)皮組織、巨核細(xì)胞、血小板等合成。血小板中含有20至25%凝血因子5。凝血因子5,作為活化凝血因子10的輔因子,成為凝血酶原復(fù)合物一員,包括活化凝血因子10、鈣離子和磷脂等,其功能在于轉(zhuǎn)化凝血酶原為凝血酶(THROMBIN;EC3.4.21.5),即活化凝血因子II(ActivatedFactorII;FactorIIa),構(gòu)成常見(common)凝血通路或機(jī)制。肝病、彌散性血管內(nèi)凝血(Disseminatedintravascularcoagulation;DIC)、原發(fā)性纖維蛋白溶解癥(primaryfibrinolysis)等引起凝血因子5減少或缺失。凝血因子5缺失將導(dǎo)致凝血酶原時(shí)間(prothrombintime;PT)和活化部分凝血活酶時(shí)間(activatedpartialthromboplastintime;APTT)延長(zhǎng),而出現(xiàn)出血體質(zhì)。活化凝血因子X(FXa)及其輔因子活化凝血因子(FVa)一起,在鈣離子和磷脂的參與下,使凝血酶原(prothrombin)轉(zhuǎn)化為凝血酶(thrombin)基于由此水解人工合成的多肽化合物底物H-D-Phe-Pip-Arg-pNA(HD-苯丙氨酰-pipecolyl-精氨酰對(duì)硝基苯胺),釋放有色對(duì)硝基苯胺,在分光光度儀(405nm波長(zhǎng))下,測(cè)定吸光峰值的變化,來定量測(cè)定活化凝血因子V的活性。其反應(yīng)系統(tǒng)為:
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50489.1活化凝血因子5(FACTOR Va)活性比色法
- 主要用途活化凝血因子5(FACTORVa)活性比色法定量檢測(cè)試劑是一種旨在通過活化凝血因子X(FXa)及其輔因子活化凝血因子(FVa),激活凝血酶,進(jìn)而水解多肽化合物底物H-D-Phe-Pip-Arg-pNA,釋放黃色對(duì)硝基苯胺,產(chǎn)生吸光峰值的變化,即采用比色法來測(cè)定血液樣品中活化凝血因子活性的權(quán)威而經(jīng)典的技術(shù)方法。該技術(shù)經(jīng)過精心研制、成功實(shí)驗(yàn)證明的。其適用于各種血漿樣品(動(dòng)物、人體等)活化凝血因子5的活性檢測(cè)。產(chǎn)品嚴(yán)格無菌,即到即用,操作簡(jiǎn)捷,性能穩(wěn)定。技術(shù)背景凝血因子5(FactorV)是維生素K非依賴性的不穩(wěn)定性單鏈糖蛋白,由肝組織、內(nèi)皮組織、巨核細(xì)胞、血小板等合成。血小板中含有20至25%凝血因子5。凝血因子5,作為活化凝血因子10的輔因子,成為凝血酶原復(fù)合物一員,包括活化凝血因子10、鈣離子和磷脂等,其功能在于轉(zhuǎn)化凝血酶原為凝血酶(THROMBIN;EC3.4.21.5),即活化凝血因子II(ActivatedFactorII;FactorIIa),構(gòu)成常見(common)凝血通路或機(jī)制。肝病、彌散性血管內(nèi)凝血(Disseminatedintravascularcoagulation;DIC)、原發(fā)性纖維蛋白溶解癥(primaryfibrinolysis)等引起凝血因子5減少或缺失。凝血因子5缺失將導(dǎo)致凝血酶原時(shí)間(prothrombintime;PT)和活化部分凝血活酶時(shí)間(activatedpartialthromboplastintime;APTT)延長(zhǎng),而出現(xiàn)出血體質(zhì)。活化凝血因子X(FXa)及其輔因子活化凝血因子(FVa)一起,在鈣離子和磷脂的參與下,使凝血酶原(prothrombin)轉(zhuǎn)化為凝血酶(thrombin)基于由此水解人工合成的多肽化合物底物H-D-Phe-Pip-Arg-pNA(HD-苯丙氨酰-pipecolyl-精氨酰對(duì)硝基苯胺),釋放有色對(duì)硝基苯胺,在分光光度儀(405nm波長(zhǎng))下,測(cè)定吸光峰值的變化,來定量測(cè)定活化凝血因子V的活性。其反應(yīng)系統(tǒng)為:[詳細(xì)]
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2018-11-08 10:00
產(chǎn)品樣冊(cè)
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人類凝血因子(Human Factor IXa β)HFIXa 1080說明書
- EnzymeResearch是一家擁有超過25年的酶研究的實(shí)驗(yàn)室,生產(chǎn)和開發(fā)多種用于基本凝血研究的多種酶和輔因子。在過去的十年EnzymeResearchLaboratories為科學(xué)家參與止血和血栓形成的研究提供了寶貴支持。EnzymeResearch通過不斷追求產(chǎn)品的Z高品質(zhì),贏得了世界各地凝血研究實(shí)驗(yàn)室的信任。HumanFactorIXaβHFIXa1080HumanFactorIXaβPreparedfromHumanFactorIXbyactivationwithBovineFactorXIa.ThisBovineFactorXIaisremovedafteractivation.CompleteactivationisobservedbySDS-PAGE.TheFactorXIaactivatesFactorIXinatwo-stepreaction.Inthefirststep,aninternalArg-Alabondiscleaved,andinthesecondstep,anArg-Valbondiscleaved.ThesecondcleavageleadstotheliberationofanactivationpeptidefromtheNH2-terminalportionoftheheavychaintoproduceFactorIXaβ.Buffercomposition=20mMTris-HCl/0.1MNaCl/pH7.4*ExtinctionCoefficient(1%)=14.3Oneunit=5gMolecularWeight=45,000daltons上海起福生物科技有限公司聯(lián)系人:楊建輝400電話:4006551678辦公電話:021-50724187傳真:021-50724961*8006手機(jī):15921799099企業(yè)QQ:4006551678網(wǎng)址:http://www.qfbio.com/地址:上海市浦東新區(qū)繡川路561號(hào)1102室[詳細(xì)]
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2018-09-29 10:03
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人凝血因子Human Factor XII (HFXII 1212)說明書
- EnzymeResearch,EnzymeResearch介紹,EnzymeResearch代理,EnzymeResearch總代,EnzymeResearch**代理,EnzymeResearchZG代理EnzymeResearch是一家擁有超過25年的酶研究的實(shí)驗(yàn)室,生產(chǎn)和開發(fā)多種用于基本凝血研究的多種酶和輔因子。在過去的十年EnzymeResearchLaboratories為科學(xué)家參與止血和血栓形成的研究提供了寶貴支持。EnzymeResearch通過不斷追求產(chǎn)品的Z高品質(zhì),贏得了世界各地凝血研究實(shí)驗(yàn)室的信任。EnzymeResearchLaboratories為生物技術(shù)公司,制藥行業(yè)、醫(yī)院和大學(xué)的研究實(shí)驗(yàn)室提供用于全方位的純化抗凝因子。除了其制造能力,EnzymeResearchLaboratories也創(chuàng)新研發(fā)領(lǐng)域中的血液凝固技術(shù)。HumanFactorXIIHFXII1212HumanFactorXII(HagemanFactor)Purifiedfromfreshfrozenhumanplasma.HumanFactorXIIispartofthecontactactivationsystem.HumanFactorXIIisasinglechainglycoproteinwithamolecularweightofabout80,000.Onceactivated,principallyfromtheactionofkallikrein,FactorXIIisconvertedintoanactiveserineprotease(Factorα-Xlla)thatfunctionsintheinvivoinitiationofbloodcoagulation,fibrinolysis,andkininformation.HumanFactorXIIhasbeenpurifiedbyionexchangechromatography.ProteinpurityisdeterminedbySDS-PAGEandactivityisdeterminedviaclottingassay.Buffercomposition=4mMSodiumAcetate-HCl/0.15MNaCl/pH5.3*ExtinctionCoefficient(1%)=14.1MolecularWeight=80,000daltons上海起福生物科技有限公司聯(lián)系人:楊建輝400電話:4006551678辦公電話:021-50724187傳真:021-50724961*8006手機(jī):15921799099企業(yè)QQ:4006551678網(wǎng)址:http://www.qfbio.com/地址:上海市浦東新區(qū)繡川路561號(hào)1102室[詳細(xì)]
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2018-09-29 10:03
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人凝血因子(Human Factor XIII)HFXIII 1313說明書
- EnzymeResearch,EnzymeResearch介紹,EnzymeResearch代理,EnzymeResearch總代,EnzymeResearch**代理,EnzymeResearchZG代理EnzymeResearch是一家擁有超過25年的酶研究的實(shí)驗(yàn)室,生產(chǎn)和開發(fā)多種用于基本凝血研究的多種酶和輔因子。在過去的十年EnzymeResearchLaboratories為科學(xué)家參與止血和血栓形成的研究提供了寶貴支持。EnzymeResearch通過不斷追求產(chǎn)品的Z高品質(zhì),贏得了世界各地凝血研究實(shí)驗(yàn)室的信任。HumanFactorXIIIHFXIII1313HumanFactorXIII(FibrinStabilizingFactor)HumanFactorXIIIisatetramercomposedoftwopairsofchainsheldtogetherbynoncovalentbonds.AfteractivationofthezymogenviaThrombintoitsactiveenzymeform,FactorXIIIaisresponsibleforcatalyzingtheformationofcovalentbridgesbetweenfibrinunitstoincreasetheelasticityoftheclotnetwork.Theresultingcross-linkedfibrinisveryinsolubleandresistanttolysis.Buffercomposition=50mMTris-HCl/0.1MNaCl/1mMEDTA/10u/mLaprotinin/20%glycerol/pH7.5*ExtinctionCoefficient(1%)=13.8MolecularWeight=320,000daltons上海起福生物科技有限公司聯(lián)系人:楊建輝400電話:4006551678辦公電話:021-50724187傳真:021-50724961*8006手機(jī):15921799099企業(yè)QQ:4006551678網(wǎng)址:http://www.qfbio.com/地址:上海市浦東新區(qū)繡川路561號(hào)1102室[詳細(xì)]
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2018-09-29 10:03
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人類凝血因子(Human Factor X)HFX 1010說明書
- EnzymeResearch,EnzymeResearch介紹,EnzymeResearch代理,EnzymeResearch總代,EnzymeResearch**代理,EnzymeResearchZG代理EnzymeResearchLaboratories為生物技術(shù)公司,制藥行業(yè)、醫(yī)院和大學(xué)的研究實(shí)驗(yàn)室提供用于全方位的純化抗凝因子。除了其制造能力,EnzymeResearchLaboratories也創(chuàng)新研發(fā)領(lǐng)域中的血液凝固技術(shù)。HumanFactorXHFX1010HumanFactorX(StuartProwerFactor)Preparedfromfreshfrozenhumanplasma.ThepurityofthisVitaminKdependentproteinisdeterminedbySDS-PAGEandshowstotalreductionuponincubationwith2-mercaptoethanol.Activityisdeterminedviaclottingassay.HumanFactorX,onceactivatedviatheContactFactorPathwayortheTissueFactorPathway,isresponsiblefortheconversionofProthrombintoThrombin.Buffercomposition20mMTris-HCl/0.1MNaCl/1mMBenzamidine/pH7.4*ExtinctionCoefficient(1%)=11.6Oneunit=8gMolecularWeight=58,800daltons上海起福生物科技有限公司聯(lián)系人:楊建輝400電話:4006551678辦公電話:021-50724187傳真:021-50724961*8006手機(jī):15921799099企業(yè)QQ:4006551678網(wǎng)址:http://www.qfbio.com/地址:上海市浦東新區(qū)繡川路561號(hào)1102室[詳細(xì)]
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2018-09-29 10:03
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人凝血因子X-GD(Human Factor X-GD)HFX-GD 說明書
- EnzymeResearch,EnzymeResearch介紹,EnzymeResearch代理,EnzymeResearch總代,EnzymeResearch**代理,EnzymeResearchZG代理EnzymeResearch是一家擁有超過25年的酶研究的實(shí)驗(yàn)室,生產(chǎn)和開發(fā)多種用于基本凝血研究的多種酶和輔因子。在過去的十年EnzymeResearchLaboratories為科學(xué)家參與止血和血栓形成的研究提供了寶貴支持。HumanFactorX-GDHFX-GDHumanFactorXDes-GlaFactorX-gladomainlesswaspreparedfromplasmapurifiedHumanFactorXusingalpha-chymotrypsin.Thealpha-chymotrypsinandallotherproductswereremovedusingananionexchangecolumnafterdigestion.Purityis>95%bySDS-PAGE.ProteinconcentrationisdeterminedbyBCA.Buffercomposition100mMTris-HCl/50mMNaCl/pH7.5MolecularWeight~57,300daltons上海起福生物科技有限公司聯(lián)系人:楊建輝400電話:4006551678辦公電話:021-50724187傳真:021-50724961*8006手機(jī):15921799099企業(yè)QQ:4006551678網(wǎng)址:http://www.qfbio.com/地址:上海市浦東新區(qū)繡川路561號(hào)1102室[詳細(xì)]
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2018-09-29 10:03
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人凝血因子Ⅶ(Human Factor VII) HFVII 1007 說明書
- EnzymeResearchLaboratories為生物技術(shù)公司,制藥行業(yè)、醫(yī)院和大學(xué)的研究實(shí)驗(yàn)室提供用于全方位的純化抗凝因子。除了其制造能力,EnzymeResearchLaboratories也創(chuàng)新研發(fā)領(lǐng)域中的血液凝固技術(shù)。EnzymeResearch的產(chǎn)品線包括:從人類和牛等離子體純化酶原激活酶凝血因子的單克隆和多克隆抗體檢測(cè)凝血因子ELISA試劑自定義的肽和蛋白質(zhì)純化服務(wù)HumanFactorVIIHFVII1007HumanFactorVII(Proconvertin)Preparedfromfreshfrozenhumanplasma.HumanFactorVIIisasingle-chainvitaminKdependentglycoproteinfoundintracequantitiesinplasma(0.5mg/Liter).IntheTissueFactorPathwayofcoagulation,HumanFactorVlla,inthepresenceofcalciumionsandtissuefactor,activatesFactorsIXandXtotheirenzymaticallyactiveforms,FactorIXaandXa.Buffercomposition=20mMTris-HCl/0.1MNaCl/1mMBenzamidine/pH7.4*ExtinctionCoefficient(1%)=13.9MolecularWeight=50,000daltons上海起福生物科技有限公司聯(lián)系人:楊建輝400電話:4006551678辦公電話:021-50724187傳真:021-50724961*8006手機(jī):15921799099企業(yè)QQ:4006551678網(wǎng)址:http://www.qfbio.com/地址:上海市浦東新區(qū)繡川路561號(hào)1102室[詳細(xì)]
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2018-09-29 10:03
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牛凝血因子X(Bovine Factor X)BFX 1006說明書
- EnzymeResearch,EnzymeResearch介紹,EnzymeResearch代理,EnzymeResearch總代,EnzymeResearch**代理,EnzymeResearchZG代理EnzymeResearch是一家擁有超過25年的酶研究的實(shí)驗(yàn)室,生產(chǎn)和開發(fā)多種用于基本凝血研究的多種酶和輔因子。在過去的十年EnzymeResearchLaboratories為科學(xué)家參與止血和血栓形成的研究提供了寶貴支持。BovineFactorXBFX1006BovineFactorXPreparedfromfreshlycollectedBovineplasma.TheproteinpurityisdeterminedbySDS-PAGEandshowstotalreductionuponincubationwith2-mercaptoethanol.BovineFactorX,whenactivatedviathecontactfactorpathwayortissuefactorpathway,isresponsiblefortheconversionofProthrombintoThrombin.Buffercomposition=20mMTris-HCl/0.1MNaCl/1mMBenzamidine/pH7.4*ExtinctionCoefficient(1%)=12.5Oneunit=10gMolecularWeight=55,000daltons上海起福生物科技有限公司聯(lián)系人:楊建輝400電話:4006551678辦公電話:021-50724187傳真:021-50724961*8006手機(jī):15921799099企業(yè)QQ:4006551678網(wǎng)址:http://www.qfbio.com/地址:上海市浦東新區(qū)繡川路561號(hào)1102室[詳細(xì)]
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2018-09-29 10:03
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Bovine Factor IX(牛凝血因子IX)BFIX 1005 說明書
- EnzymeResearch,EnzymeResearch介紹,EnzymeResearch代理,EnzymeResearch總代,EnzymeResearch**代理,EnzymeResearchZG代理EnzymeResearch是一家擁有超過25年的酶研究的實(shí)驗(yàn)室,生產(chǎn)和開發(fā)多種用于基本凝血研究的多種酶和輔因子。在過去的十年EnzymeResearchLaboratories為科學(xué)家參與止血和血栓形成的研究提供了寶貴支持。BovineFactorIXBFIX1005BovineFactorIXPreparedfromfreshlycollectedbovineplasma.ProteinpurityisdeterminedbySDS-PAGEandshowsnoreductionuponincubationwith2-mercaptoethanol.ActivatedFactorIXviafactorXlaorthefactorVIIa/tissuefactor/phospholipidcomplex,isresponsiblefortheactivationofFactorXtoXa.Buffercomposition=20mMTris-HCl/0.1MNaCl/1mMBenzamidine/pH7.4*ExtinctionCoefficient(1%)=14.9Oneunit=5gMolecularWeight=55,400daltons上海起福生物科技有限公司聯(lián)系人:楊建輝400電話:4006551678辦公電話:021-50724187傳真:021-50724961*8006手機(jī):15921799099企業(yè)QQ:4006551678網(wǎng)址:http://www.qfbio.com/地址:上海市浦東新區(qū)繡川路561號(hào)1102室[詳細(xì)]
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2018-09-29 10:03
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人凝血因子XIIIa(Human Factor XIIIa)HFXIIIa 1314說明書
- EnzymeResearch,EnzymeResearch介紹,EnzymeResearch代理,EnzymeResearch總代,EnzymeResearch**代理,EnzymeResearchZG代理EnzymeResearch是一家擁有超過25年的酶研究的實(shí)驗(yàn)室,生產(chǎn)和開發(fā)多種用于基本凝血研究的多種酶和輔因子。在過去的十年EnzymeResearchLaboratories為科學(xué)家參與止血和血栓形成的研究提供了寶貴支持。EnzymeResearch通過不斷追求產(chǎn)品的Z高品質(zhì),贏得了世界各地凝血研究實(shí)驗(yàn)室的信任。HumanFactorXIIIaHFXIIIa1314HumanFactorXIIIaHumanFactorXIIIiscleavedwithhumanalphathrombin.Thethrombinissubsequentlyremovedviachromatography.TheaboveproteinwaspurifiedfromHumanplasmathatwastestedandfoundnegativebyFDAacceptedmethodsfroAnti-HIV1/2,Anti-HTLVI&II,HBsAg,Anti-HCV,Syphilis,ABCab,HIV-1p24AgorHIV-1RNA,HCVRNAandHBVRNA.DonorsarescreenedforCJD(Creutzfeldt-JakobDisease).Buffercomposition=50mMTris/100mMNaCl/1mMEDTA/10u/mLaprotinin/50uMDTT/50%glycerol/pH7.5*ExtinctionCoefficient(1%)=13.8MolecularWeight=312,000daltons[詳細(xì)]
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2018-09-29 10:03
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人凝血因子XIa(Human Factor XIa)HFXIa 1111a 說明書
- EnzymeResearch,EnzymeResearch介紹,EnzymeResearch代理,EnzymeResearch總代,EnzymeResearch**代理,EnzymeResearchZG代理EnzymeResearch是一家擁有超過25年的酶研究的實(shí)驗(yàn)室,生產(chǎn)和開發(fā)多種用于基本凝血研究的多種酶和輔因子。在過去的十年EnzymeResearchLaboratories為科學(xué)家參與止血和血栓形成的研究提供了寶貴支持。EnzymeResearch通過不斷追求產(chǎn)品的Z高品質(zhì),贏得了世界各地凝血研究實(shí)驗(yàn)室的信任。HumanFactorXIaHFXIa1111aHumanFactorXIaPreparedfromHumanFactorXIusingHumanFactorXlla.ThisXllawasremovedusingacorntrypsininhibitorcolumn.CompleteactivationisobservedbySDS-PAGE.FactorXI,throughthecontactfactorpathwaycascade,isactivatedtoFactorXIaviaFactorXllaandHighMolecularWeightKininogen.DuringactivationbyFactorXllaandHK,FXIundergoesproteolyticcleavageinwhichtheMr=80,000chainreportedlyiscleavedtoaheavyandlightchainwithMrofabout48,000and33,000.ThisFactorXIaisresponsiblefortheactivationofFactorIXtoFactorIXa.UnlikeotherexamplesofactivationofVitaminK-dependentblood-clottingproteins,FactorXIaproteolysisofFactorIXdoesnotrequiremembranesurfaces.Buffercomposition=4mMSodiumAcetate-HCl/0.15MNaCl/pH5.3*ExtinctionCoefficient(1%)=13.1MolecularWeight=160,000daltons上海起福生物科技有限公司聯(lián)系人:楊建輝400電話:4006551678辦公電話:021-50724187傳真:021-50724961*8006手機(jī):15921799099企業(yè)QQ:4006551678網(wǎng)址:http://www.qfbio.com/地址:上海市浦東新區(qū)繡川路561號(hào)1102室[詳細(xì)]
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2018-09-29 10:03
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人類凝血因子Xa Human Factor Xa(HFXa 1011)說明書
- EnzymeResearch,EnzymeResearch介紹,EnzymeResearch代理,EnzymeResearch總代,EnzymeResearch**代理,EnzymeResearchZG代理EnzymeResearch是一家擁有超過25年的酶研究的實(shí)驗(yàn)室,生產(chǎn)和開發(fā)多種用于基本凝血研究的多種酶和輔因子。在過去的十年EnzymeResearchLaboratories為科學(xué)家參與止血和血栓形成的研究提供了寶貴支持。EnzymeResearch通過不斷追求產(chǎn)品的Z高品質(zhì),贏得了世界各地凝血研究實(shí)驗(yàn)室的信任。HumanFactorXaHFXa1011HumanFactorXaHumanFactorXaispreparedfromHumanFactorXbyactivationwithRussell'sViperVenom.ThisRVV-Xisremovedafteractivation.CompleteactivationisobservedbySDS-PAGE.FactorXaalongwithcofactorVa,phospholipidsandcalciumions,(theprothrombinasecomplex)catalyzestherapidconversionofprothrombintothrombin.Buffercomposition=20mMBisTris/0.7MNaCl/pH6.0*ExtinctionCoefficient(1%)=11.6Oneunit=8gMolecularWeight=46,000daltonsAlsoavailable:HumanFactorXaβ,des-GlaXaβandXainactivated上海起福生物科技有限公司聯(lián)系人:楊建輝400電話:4006551678辦公電話:021-50724187傳真:021-50724961*8006手機(jī):15921799099企業(yè)QQ:4006551678網(wǎng)址:http://www.qfbio.com/地址:上海市浦東新區(qū)繡川路561號(hào)1102室[詳細(xì)]
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2018-09-29 10:03
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人凝血因子XI(Human Factor XI)HFXI 1111 說明書
- EnzymeResearch是一家擁有超過25年的酶研究的實(shí)驗(yàn)室,生產(chǎn)和開發(fā)多種用于基本凝血研究的多種酶和輔因子。在過去的十年EnzymeResearchLaboratories為科學(xué)家參與止血和血栓形成的研究提供了寶貴支持。EnzymeResearch通過不斷追求產(chǎn)品的Z高品質(zhì),贏得了世界各地凝血研究實(shí)驗(yàn)室的信任。HumanFactorXIHFXI1111HumanFactorXI(PlasmaThromboplastinAntecedent)Preparedfromfreshfrozenhumanplasma.HumanFactorXIisatwo-chainglycoproteinwithmolecularweightof160,000daltons.Thetwochainsareidenticaldisulfidebondedpolypeptideswithmolecularweightsof80,000daltons.FactorXIisactivatedtoFactorXIabyFactorXlla.PurityofFactorXIisassessedbySDS-PAGE.Activityisdeterminedbyclottingassay.Buffercomposition=4mMSodiumAcetate-HCl/0.15MNaCI/pH5.3*ExtinctionCoefficient(1%)=13.1MolecularWeight=160,000daltons上海起福生物科技有限公司聯(lián)系人:楊建輝400電話:4006551678辦公電話:021-50724187傳真:021-50724961*8006手機(jī):15921799099企業(yè)QQ:4006551678網(wǎng)址:http://www.qfbio.com/地址:上海市浦東新區(qū)繡川路561號(hào)1102室[詳細(xì)]
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2018-09-29 10:03
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人類凝血因子IX Human Factor IX (HFIX 1009)說明書
- EnzymeResearch,EnzymeResearch介紹,EnzymeResearch代理,EnzymeResearch總代,EnzymeResearch**代理,EnzymeResearchZG代理EnzymeResearch是一家擁有超過25年的酶研究的實(shí)驗(yàn)室,生產(chǎn)和開發(fā)多種用于基本凝血研究的多種酶和輔因子。在過去的十年EnzymeResearchLaboratories為科學(xué)家參與止血和血栓形成的研究提供了寶貴支持。EnzymeResearch通過不斷追求產(chǎn)品的Z高品質(zhì),贏得了世界各地凝血研究實(shí)驗(yàn)室的信任。HumanFactorIXHFIX1009HumanFactorIX(ChristmasFactor)Preparedfromfreshfrozenhumanplasma.ThisproteinpurityisdeterminedbySDS-PAGEandshowsnoreductionuponincubationwith2-mercaptoethanol.Activityisdeterminedviaclottingassay.HumanFactorIX,activatedbyeithertheContactorTissueFactorPathway,isresponsiblefortheactivationofFactorXtoXa.Buffercomposition:20mMTris-HCl/0.1MNaCl/1mMBenzamidine/pH7.4*ExtinctionCoefficient(1%)=13.2Oneunit=5gMolecularWeight=56,000daltons上海起福生物科技有限公司聯(lián)系人:楊建輝400電話:4006551678辦公電話:021-50724187傳真:021-50724961*8006手機(jī):15921799099企業(yè)QQ:4006551678網(wǎng)址:http://www.qfbio.com/地址:上海市浦東新區(qū)繡川路561號(hào)1102室[詳細(xì)]
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2018-09-29 10:03
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