Determining RNA solution structure by segmental isotopic labe領 and NMR:Application to Caenorhabditis elegans spliced leader RNA 1 ABSTRACT Recent developments in multidimensional heteronuclear NMR spectroscopy and large-scale synthesis of uniformly C-and N-labeled oligonucleotides have greatly improved the prospects for determination of the solution structure of RNA. 超聲波破碎儀 S-250D