<![CDATA[<tr id="njnnr"></tr>]]>
<![CDATA[<thead id="njnnr"><acronym id="njnnr"></acronym></thead>]]>
資料庫
儀器網(wǎng) >
資料庫 >Characterization of Monoclonal Antibodies Using Capillary Electrophoresis-Electrospray Ionization-Mass Spectrometry (CE-ESI-MS)
Characterization of Monoclonal Antibodies Using Capillary Electrophoresis-Electrospray Ionization-Mass Spectrometry (CE-ESI-MS)
本文由 安捷倫科技（中國）有限公司 整理匯編
2020-05-08 14:45 453閱讀次數(shù)
文檔僅可預(yù)覽首頁內(nèi)容，請下載后查看全文信息！
立即下載
This Application Note demonstrates the utility of capillary electrophoresis/mass spectrometry (CE/MS) for the analysis of intact monoclonal antibodies (mAbs). The Agilent 7100 CE System coupled to an Agilent 6530 Q-TOF LC/MS was used to study the intact and reduced forms of mAbs. The combination of mass measurements obtained by CE/MS and the data processing capabilities of Agilent?MassHunter and BioConfi rm Software enables the identifi cation of heterogeneity in an intact mAb and its fragments. The result demonstrates the utility of CE/MS as a complementary technique to liquid chromatography/mass spectrometry (LC/MS) for the analysis of mAbs.
登錄或新用戶注冊
請用手機(jī)微信掃描下方二維碼登錄 或注冊新賬號
微信掃碼，手機(jī)電腦聯(lián)動
更多資料
Characterization of Monoclonal Antibodies Using Capillary Electrophoresis-Electrospray Ionization-Mass Spectrometry (CE-ESI-MS) This Application Note demonstrates the utility of capillary electrophoresis/mass spectrometry (CE/MS) for the analysis of intact monoclonal antibodies (mAbs). The Agilent 7100 CE System coupled to an Agilent 6530 Q-TOF LC/MS was used to study the intact and reduced forms of mAbs. The combination of mass measurements obtained by CE/MS and the data processing capabilities of Agilent?MassHunter and BioConfi rm Software enables the identifi cation of heterogeneity in an intact mAb and its fragments. The result demonstrates the utility of CE/MS as a complementary technique to liquid chromatography/mass spectrometry (LC/MS) for the analysis of mAbs.[詳細(xì)]
2020-05-08 14:45
應(yīng)用文章
Heterogeneity of Monoclonal Antibodies Revealed by C Heterogeneity of Monoclonal Antibodies Revealed by C[詳細(xì)]
2024-09-14 19:11
標(biāo)準(zhǔn)
Enantioseparation in capillary electrophoresis using Enantioseparation in capillary electrophoresis using[詳細(xì)]
2024-09-28 21:25
報(bào)價單
PROTEIN CHARACTERIZATION USING DYNAMIC AND STATIC LI PROTEIN CHARACTERIZATION USING DYNAMIC AND STATIC LI[詳細(xì)]
2024-09-29 07:56
操作手冊
Analysis of Antibody-Drug Conjugates Using Size Exclusion Chromatography and Mass Spectrometry Recombinant monoclonal antibodies (mAbs) have emerged as important therapeutic agents for the treatment of different diseases. This technology has been extended by the development of antibody drug conjugates (ADCs). [詳細(xì)]
2016-07-21 00:00
標(biāo)準(zhǔn)
Characterization of lgG Glycosylation Using Intact Protein Analysis and Peptide Mapping Characterization of lgG Glycosylation Using Intact Protein Analysis and Peptide Mapping[詳細(xì)]
2024-10-04 06:42
選購指南
CE-ICPMS spectrometry 2 CE-ICPMS spectrometry 2[詳細(xì)]
2011-10-07 00:00
應(yīng)用文章
CE-ICPMS spectrometry 1 CE-ICPMS spectrometry 1[詳細(xì)]
2011-10-07 00:00
應(yīng)用文章
Evaluation of Tandem Mass Spectrometry Evaluation of Tandem Mass Spectrometry[詳細(xì)]
2024-09-20 00:04
專利
Circular Dichroism Spectrometry For the Analysis of Circular Dichroism Spectrometry For the Analysis of[詳細(xì)]
2024-09-29 04:13
產(chǎn)品樣冊
Green Mountain Antibodies Zxin報(bào)價 Isohelix是CellProjectsLtd的技術(shù)部門，專門為生命科學(xué)研究，分子診斷和法醫(yī)市場開發(fā)和制造創(chuàng)新的高品質(zhì)DNA取樣和純化產(chǎn)品。產(chǎn)品包括DNA拭子，DNA唾液收集裝置和許多DNA分離，穩(wěn)定和相關(guān)試劑盒。Cell項(xiàng)目采取更廣泛的方法，而支持Isohelix也制造用于電穿孔，PCR，qPCR，轉(zhuǎn)染和電泳的產(chǎn)品。Cell項(xiàng)目和Isohelix品牌產(chǎn)品直接銷售并通過分銷商銷售。從唾液中采集DNA簡便無創(chuàng)可靠GeneFix系列DNA產(chǎn)品設(shè)計(jì)用于使從唾液中收集并經(jīng)過穩(wěn)定化的DNA產(chǎn)量和純度Zda化，專門設(shè)計(jì)用于保存和穩(wěn)定1或2毫升唾液樣品中的DNA。由此經(jīng)GeneFix采集的DNA可用于Z嚴(yán)格的下游過程。收集管可以承受指定的防泄漏樣品運(yùn)輸?shù)奈锢韷毫?，并設(shè)計(jì)了印刷條碼，蓋子也適用于自動去蓋機(jī)，可用于手動或更自動化的應(yīng)用。主要優(yōu)勢預(yù)填充穩(wěn)定化緩沖液，使用方便。獨(dú)特的漏斗設(shè)計(jì)，防止緩沖液溢出。室溫下DNA可穩(wěn)定保存至少60個月*至少60個月內(nèi)可以保證DNA的產(chǎn)量穩(wěn)定*2毫升唾液中的總DNA產(chǎn)量可超過100微克。3種GeneFix分離試劑盒可以無縫對接。唾液制備試劑盒引起的RNA污染超低。本裝置與手動和高通量試劑盒兼容。在大多數(shù)下游應(yīng)用中進(jìn)行了全面測試。在指定的95kPa氣壓下可防漏郵寄和退貨技術(shù)性DNA資料為其提供廣泛支持。在正在進(jìn)行的、持續(xù)的嚴(yán)格測試中。采集方法比較為什么使用唾液收集DNA？DNA產(chǎn)量更高，達(dá)到10ug，Z高可達(dá)100ugDNA即時穩(wěn)定化可用于更復(fù)雜的重復(fù)性分析更大量DNA的保存有些人偏愛使用唾液而非血液樣品采集拓展市場規(guī)模產(chǎn)品信息每個包裝中有2、12和50個GFX收集裝置，可收集1或2毫升唾液每個GeneFix裝置包括一個收集管，內(nèi)含集成型穩(wěn)定化緩沖液、可能有拭子、漏斗和使用說明書。配件手動或自動收集管預(yù)印條形碼用于裂解步驟的蛋白酶KCellProjects公司于2007年5月通過英國和歐盟（BSEN）ISO9001：2000質(zhì)量認(rèn)證，可從事分子生物學(xué)溶液的供應(yīng)和生產(chǎn)，也通過了BSENISO13485：2003認(rèn)證，可從事用于體外診斷試劑盒的裝置的供應(yīng)和生產(chǎn)。我們公司Zda優(yōu)勢是強(qiáng)大的采購，1：基本什么都能進(jìn)口，血清，抗體，耗材，還有部分限制進(jìn)口的，2：貨品全，現(xiàn)經(jīng)營過700多個品牌，基本所有生物試劑耗材都可以進(jìn)口，特別是冷偏的產(chǎn)品那就更有優(yōu)勢，3：提供加急服務(wù)，一般1-2周到貨，超過時限加急費(fèi)全免4：價格公道，絕大部分價格有優(yōu)勢，當(dāng)然不能保證1**%產(chǎn)品都是價格Zdi,因?yàn)閮r格Zdi意味著沒有服務(wù).5：良好的信譽(yù)，大部分客戶我們提供貨到付款服務(wù)，客戶包括清華，北大交大復(fù)旦，中山等100多所大學(xué)，ROCHE，阿斯利康，國藥，fisher等500多家公司6：我們du家代理的品牌有：AntibodyResearchCorporation，arcticzymes，Biorelevant，AmberGen,Inc.，clemente-associates，clodronateliposomes，ColumbiaBiosciences，enzymeresearch，GeneBridgesGmbH，Genovis，AmberGen,Inc.BiotechnologyGmbH，HaematologicTechnologiesHTIHaemtech，hookelabs，Immudex，InnovativeResearchofAmerica，inspiralis，ListBiologicalLaboratories,Inc.，lumafluor，Microsurfaces，multiplicom，nanotools，Pel-FreezBiologicals，pentapharm，progen，ProteinArk，QA-Bio,Inc，QA-Bio,IncQuickZymeBiosciences，Teknova，TriLinkBioTechnologies,Inc.，ZyagenLaboratories等7：我們還是invitrogen,qiagen,MidlandBioProductsCorporationam,sigma;neb,roche,merck,rnd,BD,GE,pierce,BioLegend等知名批發(fā)，歡迎合作。[詳細(xì)]
2018-09-29 10:02
產(chǎn)品樣冊
Characterization of molybdenum Characterization of molybdenum[詳細(xì)]
2011-07-27 00:00
其它
Preparation and characterization Preparation and characterization[詳細(xì)]
2009-05-13 00:00
期刊論文
Characterization of an emulsion Characterization of an emulsion[詳細(xì)]
2024-09-11 17:57
報(bào)價單
Detection of paracetamol by capillary electrophoresi Detection of paracetamol by capillary electrophoresi[詳細(xì)]
2007-06-21 00:00
標(biāo)準(zhǔn)
Capillary Tube 2017Zxin報(bào)價表 世界ding級實(shí)驗(yàn)材料供應(yīng)商CellTechnology正式授權(quán)上海起發(fā)為其ZG代理，CellTechnology在一直是行業(yè)的標(biāo)桿,一直為廣大科研客戶提供Z為優(yōu)質(zhì)的產(chǎn)品和服務(wù),上海起發(fā)一直秉承為ZG科研客戶帶來**的產(chǎn)品，**的服務(wù)，簽約CellTechnology就是為了給廣大科研客戶帶來更加完善的產(chǎn)品和服務(wù),您的滿意將是我們Zda的收獲CellTechnologyZG代理,CellTechnology上海代理，CellTechnology北京代理，CellTechnology廣東代理，CellTechnology江蘇代理CellTechnology湖北代理,CellTechnology天津,CellTechnology黑龍江代理,CellTechnology內(nèi)蒙古代理,CellTechnology吉林代理,CellTechnology福建代理,CellTechnology江蘇代理,CellTechnology浙江代理,CellTechnology四川代理,美國CellTechnology(細(xì)胞工程)公司成立于1996年，提供一系列物美價廉的Caspase、NOS、ROS、線粒體膜點(diǎn)位試劑盒和輔助試劑。2017年部分產(chǎn)品Zxin報(bào)價如下：貨號品名規(guī)格價格品牌AChE100-2FluoroAChE-100tests100Tests7225CellTechnology2017AChE100-3FluoroAChE-500Tests500Tests28815CellTechnology2017ACT100-2FlowCytometryCytotoxicity-100Tests100Tests4675CellTechnology2017ADP100-2UltraPureADP1ml1mL5525CellTechnology2017ADP100-3UltraPureADP5ml5mL23375CellTechnology2017APO200-2Apo3/7HTS-100Tests100Tests4675CellTechnology2017APO200-3Apo3/7HTS-500Tests500Tests13515CellTechnology2017APO200-4Apo3/7HTS-1000Tests1000Tests24565CellTechnology2017APODNA-1DNADamageKit25Tests25Tests3825CellTechnology2017APODNA-2DNADamageKit100Tests100Tests12665CellTechnology2017CLACGMP100-2ChemiluminescentcGMPKit100Tests100Tests6375CellTechnology2017CLACHE100-2aCella-AChE100Tests100Tests6715CellTechnology2017CLACHE100-3aCella-AChE500Tests500Tests22015CellTechnology2017CLACHE100-4aCella-AChE1000Tests1000Tests37315CellTechnology2017CLACMP100-2ChemiluminescentcAMPKit100Tests100Tests5865CellTechnology2017CLATOX100-3aCella-TOX500Tests500Tests13175CellTechnology2017CLATOX100-3LaCella-TOX500Tests(with5LumiPlates)500Tests14025CellTechnology2017CLATOX100-3PaCella-TOX500Tests(with5LumiPlates+5TissueCulturePlates)500Tests14875CellTechnology2017CLATOX100-4aCella-TOX1000Tests1000Tests25415CellTechnology2017CSOD100-2ColorimetricSuperoxideDismutase100Tests3825CellTechnology2017DNACASP3-1DNACaspase3Detection25Tests25Tests4165CellTechnology2017DNACASP3-2DNACaspase3Detection100Tests100Tests7225CellTechnology2017EAD100GeneralAssayDiluent100mL935CellTechnology2017EAD100GeneralAssayDiluent500mL3315CellTechnology2017EAD100GeneralAssayDiluent1L4165CellTechnology2017EAD100GeneralAssayDiluent10L38165CellTechnology2017EAD200IgM-ReducingAssayDiluent100mL935CellTechnology2017EAD200IgM-ReducingAssayDiluent500mL3485CellTechnology2017EAD200IgM-ReducingAssayDiluent1L4335CellTechnology2017EAD200IgM-ReducingAssayDiluent10L40205CellTechnology2017EAD300NonMammalianBasedAssayDiluent100mL935CellTechnology2017EAD300NonMammalianBasedAssayDiluent500mL3485CellTechnology2017EAD300NonMammalianBasedAssayDiluent1L4335CellTechnology2017EAD300NonMammalianBasedAssayDiluent10L40205CellTechnology2017EAD400Antigen-DownAssayDiluent100mL935CellTechnology2017EAD400Antigen-DownAssayDiluent500mL3485CellTechnology2017EAD400Antigen-DownAssayDiluent1L5355CellTechnology2017EAD400Antigen-DownAssayDiluent10L49385CellTechnology2017EBB100GeneralLow-LevelBlockerwithBSA100mL680CellTechnology2017EBB100GeneralLow-LevelBlockerwithBSA500mL2125CellTechnology2017EBB100GeneralLow-LevelBlockerwithBSA1L3825CellTechnology2017EBB100GeneralLow-LevelBlockerwithBSA10L34765CellTechnology2017EBB200Nonmammalian-BasedBlockers100mL765CellTechnology2017EBB200Nonmammalian-BasedBlockers500mL2635CellTechnology2017EBB200Nonmammalian-BasedBlockers1L4675CellTechnology2017EBB200Nonmammalian-BasedBlockers10L43265CellTechnology2017EBB300SynBlockwithTweenandSyntheticBlockers100mL765CellTechnology2017EBB300SynBlockwithTweenandSyntheticBlockers500mL2295CellTechnology2017EBB300SynBlockwithTweenandSyntheticBlockers1L4165CellTechnology2017EBB300SynBlockwithTweenandSyntheticBlockers10L37315CellTechnology2017ECB1005xUniversalPlateCoatingBuffer100mL765CellTechnology2017ECB1005xUniversalPlateCoatingBuffer500mL2295CellTechnology2017ECB1005xUniversalPlateCoatingBuffer1L4505CellTechnology2017ECB1005xUniversalPlateCoatingBuffer10L42075CellTechnology2017ECD1055xMono/PolyConjugateDiluent100mL2040CellTechnology2017ECD1055xMono/PolyConjugateDiluent500mL9775CellTechnology2017ECD1055xMono/PolyConjugateDiluent1L18275CellTechnology2017ECD1055xMono/PolyConjugateDiluent10L167875CellTechnology2017ECD2055xAntigen-DownConjugateDiluent100mL2040CellTechnology2017ECD2055xAntigen-DownConjugateDiluent500mL9775CellTechnology2017ECD2055xAntigen-DownConjugateDiluent1L18275CellTechnology2017ECD2055xAntigen-DownConjugateDiluent10L167875CellTechnology2017ECD3055xPoly/PolyConjugateDiluent100mL8330CellTechnology2017ECD3055xPoly/PolyConjugateDiluent500mL33915CellTechnology2017ECD3055xPoly/PolyConjugateDiluent1L62900CellTechnology2017ECD3055xPoly/PolyConjugateDiluent10L586500CellTechnology2017ECD4055xMono/Goat-PolyConjugateDiluent100mL5015CellTechnology2017ECD4055xMono/Goat-PolyConjugateDiluent500mL15215CellTechnology2017ECD4055xMono/Goat-PolyConjugateDiluent1L25415CellTechnology2017ECD4055xMono/Goat-PolyConjugateDiluent10L220915CellTechnology2017ECD6055xConjugateStockStabilizingReagent100mL1785CellTechnology2017ECD6055xConjugateStockStabilizingReagent500mL8755CellTechnology2017ECD6055xConjugateStockStabilizingReagent1L16915CellTechnology2017ECD6055xConjugateStockStabilizingReagent10L148665CellTechnology2017ESD100GeneralSerumDiluent100mL935CellTechnology2017ESD100GeneralSerumDiluent500mL3315CellTechnology2017ESD100GeneralSerumDiluent1L4165CellTechnology2017我們公司Zda優(yōu)勢是強(qiáng)大的采購，1：基本什么都能進(jìn)口，血清，抗體，耗材，還有部分限制進(jìn)口的，2：貨品全，現(xiàn)經(jīng)營過700多個品牌，基本所有生物試劑耗材都可以進(jìn)口，特別是冷偏的產(chǎn)品那就更有優(yōu)勢，3：提供加急服務(wù)，一般1-2周到貨，超過時限加急費(fèi)全免4：價格公道，絕大部分價格有優(yōu)勢，當(dāng)然不能保證1**%產(chǎn)品都是價格Zdi,因?yàn)閮r格Zdi意味著沒有服務(wù).5：良好的信譽(yù)，大部分客戶我們提供貨到付款服務(wù)，客戶包括清華，北大交大復(fù)旦，中山等100多所大學(xué)，ROCHE，阿斯利康，國藥，fisher等500多家公司6：我們還是Santa,AdvancedBiotechnologiesInc,genebridge,bangs,BBInternational,crystalchem,dianova,FDNeurotechnologies,Inc.Dako,Inc,GePromegaridege,GlycotopeBiotechnologyGmbH;iduron,InnovativeResearchofAmerica,Ludger,neuroprobe,genebridge,Polysciences,prospecbi,QA-BIO,quickzyme,FULLERLABS,INC,sterlitech；sysy,TriLinkBioTechnologies,Inc；worthington-biochem,zyagen等幾十家國外公司授權(quán)代理。7：我們還是invitrogen,qiagen,genebridgeam,sigma;Promega,roche,merck,rnd,BD,GE,pierce,BioLegend等知名批發(fā)，歡迎合作。[詳細(xì)]
2018-10-06 10:00
產(chǎn)品樣冊
Determination of levodopa by capillary electrophores Determination of levodopa by capillary electrophores[詳細(xì)]
2024-09-28 15:02
課件
Raman Characterization of Polymers Raman Characterization of Polymers[詳細(xì)]
2015-09-22 00:00
選購指南
Characterization of polyethersulfone-polyimide hollo Characterization of polyethersulfone-polyimide hollo[詳細(xì)]
2014-05-29 00:00
標(biāo)準(zhǔn)
Raman Characterization of Polymers Raman Characterization of Polymers[詳細(xì)]
2024-09-28 09:11
期刊論文
Copyright 2004-2026 yiqi.com All Rights Reserved , 未經(jīng)書面授權(quán) , 頁面內(nèi)容不得以任何形式進(jìn)行復(fù)制
Characterization of Monoclonal Antibodies Using Capillary Electrophoresis-Electrospray Ionization-Mass Spectrometry (CE-ESI-MS)
Green Mountain Antibodies Zxin報(bào)價
Capillary Tube 2017Zxin報(bào)價表
在線留言
滬公網(wǎng)安備 31011502008050號
參與評論
登錄后參與評論